Luke Shaw, Anthony Martial, Diogo Dalot and Eric Bailly will also definitely miss the clash with the Foxes, while Jesse Lingard and Aaron Wan-Bissaka are both doubtful after withdrawing from England’s Euro 2020 qualifiers against Bulgaria and Kosovo.
Pogba twisted his ankle in the 1-1 draw at Southampton two weeks ago and did not play for France in their two matches during the international break, with the midfielder expected to return for the match at West Ham on 22 September.
Shaw (hamstring) and Martial (thigh) have still not recovered from the injuries sustained in the 2-1 defeat to Crystal Palace on 24 August, while Dalot (hip) and Bailly (knee) are longer-term injuries.
“The treatment room has been busy and it still is,” said Solskjaer. “We don’t really know who is going to be available.
“Paul will not be fit, not unless he has a miraculous recovery. He has not been ready to do training at 100%.”
United are looking for their first win since the opening day of the season with draws at Wolves and Southampton either side of the Palace defeat leaving them down in eighth, three points adrift of Leicester in third.
– Tough game –
Under former Liverpool manager Brendan Rodgers, Leicester are aiming to return to the top six at the expense of the likes of United, Chelsea, Arsenal or Tottenham, three years on from their remarkable Premier League title triumph.
“Leicester is always a tough game. They are a club that want to push into the top four, they have good players and a proven top manager,” added Solskjaer.
“Brendan’s teams always play good football, so we have to play well to get the three points.”
Leicester’s visit will mean an early reunion with his old club for Harry Maguire, who swapped the Foxes for Old Trafford this summer in an £80 million transfer that made him the world’s most expensive defender.
“Leicester did not want to lose him and that is why we spent the money we did on him.”
Solskjaer also believes Maguire has the traits that mark him out as a potential future captain of United.
“He is definitely a character and personality that can be captain of a big club.
“He is a leader in the dressing room, both in his performances, his stature and his behaviour.
“Harry is a character you would like to follow. Some are technical leaders, some are leaders by voice, but he has got the lot.”